BS. Biomarker Module

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BS001
In the past years, many participants of SHARE allowed us to tak e physical health measurements lik e their grip and lung strength. This year, to more precisely assessdisease risk , we would lik e to collect a few blood drops using just a finger prick as it is done daily by millions of diabetic people. We would be very grateful if you wouldagree to participate. This is an important part of the study, as the analysis of blood samples will tell us a lot about the health of the population. I will explain more to youabout it. Yet, this measurement is absolutely voluntary. If you do not wish to have your finger prick ed, we will leave it out and continue the interview without the biomedicalpart.Before we begin, I would lik e to have you read and sign this consent form.

IN THE PAST YEARS, MANY PARTICIPANTS OF SHARE ALLOWED US TO TAK E PHYSICAL HEALTH MEASUREMENTS LIK E THEIR GRIP AND LUNG STRENGTH. THIS YEAR, TO MORE PRECISELY ASSESSDISEASE RISK , WE WOULD LIK E TO COLLECT A FEW BLOOD DROPS USING JUST A FINGER PRICK AS IT IS DONE DAILY BY MILLIONS OF DIABETIC PEOPLE. WE WOULD BE VERY GRATEFUL IF YOU WOULDAGREE TO PARTICIPATE. THIS IS AN IMPORTANT PART OF THE STUDY, AS THE ANALYSIS OF BLOOD SAMPLES WILL TELL US A LOT ABOUT THE HEALTH OF THE POPULATION. I WILL EXPLAIN MORE TO YOUABOUT IT. YET, THIS MEASUREMENT IS ABSOLUTELY VOLUNTARY. IF YOU DO NOT WISH TO HAVE YOUR FINGER PRICK ED, WE WILL LEAVE IT OUT AND CONTINUE THE INTERVIEW WITHOUT THE BIOMEDICALPART.BEFORE WE BEGIN, I WOULD LIK E TO HAVE YOU READ AND SIGN THIS CONSENT FORM.
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BS002
IWER: Please tick

IWER: PLEASE TICK
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1 R signed the consent form
5 R did NOT sign the consent form


If IWER: Please tick (BS002) = 5 »

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BS003
Thank you. We will continue with the interview.

THANK YOU. WE WILL CONTINUE WITH THE INTERVIEW.
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1 Continue


Else

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BS004
IWER:Please enter the k ind of analyses which R does not permitType "NONE" if respondent does not mention any analyses which should not be done.

IWER:PLEASE ENTER THE K IND OF ANALYSES WHICH R DOES NOT PERMITTYPE "NONE" IF RESPONDENT DOES NOT MENTION ANY ANALYSES WHICH SHOULD NOT BE DONE.

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BS005
As I mentioned, I'd lik e to collect a small sample of your blood. I will clean your finger with an alcohol wipe, then using a small instrument I will prick your finger and collectenough blood to fill at least three small circles on the collection card. I have received a special training to conduct this measurement. If you want, you can also prick yourfinger by yourself.Do you understand the directions for this measurement?

AS I MENTIONED, I'D LIK E TO COLLECT A SMALL SAMPLE OF YOUR BLOOD. I WILL CLEAN YOUR FINGER WITH AN ALCOHOL WIPE, THEN USING A SMALL INSTRUMENT I WILL PRICK YOUR FINGER AND COLLECTENOUGH BLOOD TO FILL AT LEAST THREE SMALL CIRCLES ON THE COLLECTION CARD. I HAVE RECEIVED A SPECIAL TRAINING TO CONDUCT THIS MEASUREMENT. IF YOU WANT, YOU CAN ALSO PRICK YOURFINGER BY YOURSELF.DO YOU UNDERSTAND THE DIRECTIONS FOR THIS MEASUREMENT?
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1 Yes
5 No


If As I mentioned, I'd lik e to collect a small sample of your blood. I will clean your finger with an alcohol wipe, then using a small instrument I will prick your finger and collectenough blood to fill at least three small circles on the collection card. I have received a special training to conduct this measurement. If you want, you can also prick yourfinger by yourself.Do you understand the directions for this measurement? (BS005) = 1 Yes 5 No  »

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BS006
Tak ing the measurement is of course voluntary.From your point of view: are there any reasons which would prevent you from conducting the measurement, for example medical reasons?

TAK ING THE MEASUREMENT IS OF COURSE VOLUNTARY.FROM YOUR POINT OF VIEW: ARE THERE ANY REASONS WHICH WOULD PREVENT YOU FROM CONDUCTING THE MEASUREMENT, FOR EXAMPLE MEDICAL REASONS?
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1 Yes
5 No


| |  If Tak ing the measurement is of course voluntary.From your point of view: are there any reasons which would prevent you from conducting the measurement, for example medical reasons? (BS006) = 5 »

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BS007
May we now begin?

MAY WE NOW BEGIN?
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1 Yes
5 No


| | |  If May we now begin? (BS007) = 1 Yes 5 No  »

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BS008
IWER:Tak e dried blood spots book let and follow the instructions 1 to 15.

IWER:TAK E DRIED BLOOD SPOTS BOOK LET AND FOLLOW THE INSTRUCTIONS 1 TO 15.
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BS009
IWER:Enter barcode from barcode label into capi

IWER:ENTER BARCODE FROM BARCODE LABEL INTO CAPI

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BS010
IWER:Repeat barcodenumber

IWER:REPEAT BARCODENUMBER

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BS011
Thank you for your cooperation.This concludes the Dried Blood Spot portion of the interview.Before we continue with the interview, I need a moment to enter a few pieces of information in the computer.

THANK YOU FOR YOUR COOPERATION.THIS CONCLUDES THE DRIED BLOOD SPOT PORTION OF THE INTERVIEW.BEFORE WE CONTINUE WITH THE INTERVIEW, I NEED A MOMENT TO ENTER A FEW PIECES OF INFORMATION IN THE COMPUTER.
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BS012
IWER:What, if any, problems occured during the collection of the blood sample? {CodeAll}

IWER:WHAT, IF ANY, PROBLEMS OCCURED DURING THE COLLECTION OF THE BLOOD SAMPLE? {CODEALL}
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1 R became light-headed, fainted, or nauseous
2 R had difficulty getting finger to stop bleeding
3 Unable to obtain enough blood
4 Problem with equipment or supplies
96 None
97 Other


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BS013
BS013

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BS014
IWER:How many times did the R's finger need to be prick ed in order to fill the circles/

IWER:HOW MANY TIMES DID THE R'S FINGER NEED TO BE PRICK ED IN ORDER TO FILL THE CIRCLES/
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1 One time
2 Two times
3 Two times but the R was unable to fill all circles with blood


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BS015
IWER:How many circles on the cards could be filled?

IWER:HOW MANY CIRCLES ON THE CARDS COULD BE FILLED?
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1 1
2 2
3 3
4 4
5 5
6 6
7 No circles could be filled


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BS016
IWER:How compliant was R during this measurement?/

IWER:HOW COMPLIANT WAS R DURING THIS MEASUREMENT?/
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1 R was fully compliant
2 R was prevented from fully complying due to illness, pain, or other symptoms or discomforts
3 R was not fully compliant, but no obvious reasons for that


If (As I mentioned, I'd lik e to collect a small sample of your blood. I will clean your finger with an alcohol wipe, then using a small instrument I will prick your finger and collectenough blood to fill at least three small circles on the collection card. I have received a special training to conduct this measurement. If you want, you can also prick yourfinger by yourself.Do you understand the directions for this measurement? (BS005) = 5) or (Tak ing the measurement is of course voluntary.From your point of view: are there any reasons which would prevent you from conducting the measurement, for example medical reasons? (BS006) = 1 Yes 5 No )) or (May we now begin? (BS007) = 5) »

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BS017
IWER:Why didn't complete the blood sample? {CodeAll}/

IWER:WHY DIDN'T COMPLETE THE BLOOD SAMPLE? {CODEALL}/
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1 R felt it would not be safe
2 IWER felt it would not be safe
3 R refused or was not willing to complete the measurement
4 R did not understand the instructions
5 R has a bleeding disorder and/or takes blood thinning drugs
6 Proxy interview
97 Other reasons


Else

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BS018
IWER: Does the respondent wish to be informed about blood results in case a value is outside the normal range?/

IWER: DOES THE RESPONDENT WISH TO BE INFORMED ABOUT BLOOD RESULTS IN CASE A VALUE IS OUTSIDE THE NORMAL RANGE?/
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1 Yes
5 No